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ARN21929

SKU: orb3134967

Description

ARN21929 is a topoisomerase II (TopoisomeraseII) inhibitor with an IC50 of 4.5 μM. It exhibits favorable kinetic and thermodynamic solubility and metabolic stability. However, ARN21929 shows poor antiproliferative activity against A549, DU145, MCF7, HeLa, and A375 cells. It is useful for tumor research.

Research Area

Molecular Biology

Images & Validation

Key Properties

CAS Number2230854-98-3
MW321.35
FormulaC18H16FN5
SMILESFC=1C=CC=CC1NC2=NC(=NC3=C2CNCC3)C=4C=CN=CC4
TargetTopoisomerase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information