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Argyrin A

SKU: orb2942938

Description

Argyrin A is a cyclic peptide proteasome inhibitor with potent antitumor activity. It stabilizes the cell cycle regulator p27Kip1 by blocking its degradation, making it a valuable tool for cancer research in both cellular and animal models of tumorigenesis.

Research Area

Protein Biochemistry

Images & Validation

Key Properties

CAS Number174423-37-1
MW824.905
FormulaC40H44N10O8S
SMILESC(C=1C=2C(NC1)=CC=CC2OC)[C@@H]3NC(=O)[C@H](CC=4C=5C(NC4)=CC=CC5)NC(=O)C=6N=C(SC6)[C@@H](C)NC(=O)CN(C)C(=O)C(=C)NC(=O)[C@@H](C)NC(=O)CNC3=O
TargetProteasome

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

Protocol Information