Arg-PEG1-Dasa

SKU: orb3177205

Description

Arg-PEG1-Dasa is a mini-PROTAC that targets BCR-ABL. It is capable of inducing BCR-ABL degradation (EC50 = 0.85 nM) and demonstrates antiproliferative activity in K562 cells (IC50 = 0.36 nM). Arg-PEG1-Dasa is applicable for research in chronic myeloid leukemia.

Key Properties

• CAS Number: 3037776-67-0
• MW: 759.33
• Formula: C₃₃H₄₇ClN₁₂O₅S
• SMILES: N(C1=CC(=NC(C)=N1)N2CCN(CCOC(CCOCCNC([C@H](CCCNC(=N)N)N)=O)=O)CC2)C=3SC(C(NC4=C(C)C=CC=C4Cl)=O)=CN3
• Target: Bcr-Abl,PROTACs

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Bcr-Abl,PROTACs