AR/AR-V7-IN-1

SKU: orb2566959

Description

AR/AR-V7-IN-1 (Compound 20i) is a small molecule inhibitor of the androgen receptor and its splice variant AR-V7, with an IC50 of 172.85 nM. It demonstrates anti-proliferative activity in LNCaP and 22RV1 prostate cancer cell lines and has shown efficacy in inhibiting tumor growth in a 22RV1 xenograft model, supporting its use in prostate cancer research.

Research Area

Metabolism Research

Key Properties

• CAS Number: 2964558-54-9
• MW: 660.22
• Formula: C₃₆H₄₃ClFN₇O₂
• SMILES: N(C1CN(CCCF)C1)C2=CC=C(CC3CCN(CC3)C4=CC=C(C(N[C@@H]5CC[C@@H](OC6=CC(Cl)=C(C#N)C=C6)CC5)=O)N=N4)C=C2
• Target: Androgen Receptor

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171391464