APT STAT3

SKU: orb2563796

Description

APT STAT3 is a high-affinity, specific peptide inhibitor of STAT3 (Kd ~231 nM). It is a valuable research tool for studying STAT3-dependent oncogenesis and has been utilized in both in vitro and in vivo models to investigate cancers driven by constitutively activated STAT3 signaling.

Research Area

Cancer Biology, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• Target: STAT
• CAS Number: 1345420-96-3
• MW: 3226.56
• Formula: C₁₅₈H₂₀₅N₃₉O₃₆
• SMILES: C([C@@H](C(=O)N1[C@H](C(NCC(N[C@H](C(N[C@@H](CC=2C=3C(NC2)=CC=CC3)C(N[C@H](C(N[C@@H](CC=4C=5C(NC4)=CC=CC5)C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@@H](CC=6C=7C(NC6)=CC=CC7)C(N[C@H](C(N[C@@H](CC=8C=9C(NC8)=CC=CC9)C(N[C@H](C(NCC(N[C@H](C(N[C@@H](CC%10=CC=C(O)C=C%10)C(N[C@H](C(N[C@@H](CC%11=CC=CC=C%11)C(N[C@H](C(N[C@@H](CCCCN)C(O)=O)=O)CC(C)C)=O)=O)CCC(N)=O)=O)=O)C)=O)=O)CCCCN)=O)=O)[C@@H](C)O)=O)=O)CCCCN)=O)=O)CC(N)=O)=O)CCC(O)=O)=O)=O)[C@@H](C)O)=O)=O)CO)=O)=O)CCC1)NC([C@@H](NC([C@H](CC%12=CC=CC=C%12)NC(CNC([C@H](CC%13=CN=CN%13)N)=O)=O)=O)CCC(N)=O)=O)C=%14C=%15C(NC%14)=CC=CC%15

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171715770