Apoptosis inducer 57

SKU: orb3175136

Description

Apoptosis inducer57 is an apoptosis inducer and a thymidylate synthase (TS) inhibitor with cytotoxicity IC50 values of 15.7 µM for SW480 cancer cells and 16.5 µM for MCF-7 cancer cells. It induces dose-dependent apoptosis and S-phase cell cycle arrest. TS-IN-9 stabilizes at the TS active site through interactions with Asp218 and Met311, and is useful for research on breast and colorectal cancers.

Research Area

Cell Biology

Key Properties

• Target: Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Apoptosis