Apoptosis inducer 56

SKU: orb3210344

Description

Apoptosis inducer56 is an apoptosis inducer that binds to DNA minor grooves, causing DNA damage through the upregulation of γH2AX and p-ATM expression. This compound induces endogenous apoptosis by causing S phase cell cycle arrest and increasing the p53 and Bax/Bcl-2 ratios, as well as promoting caspase-7 cleavage. It demonstrates higher selectivity for cancer cells compared to normal breast epithelial cells and is useful in breast cancer research.

Key Properties

• CAS Number: 952306-31-9
• MW: 271.34
• Formula: C₁₁H₁₇N₃O₃S
• SMILES: O=C(NO)CCCCCCC(=O)NC1=NC=CS1
• Target: Caspase,DNA/RNA Synthesis,MDM-2/p53,Bcl-2 Family,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Caspase,DNA/RNA Synthesis,MDM-2/p53,Bcl-2 Family,Apoptosis