Apoptosis inducer 45

SKU: orb3173209

Description

Apoptosis inducer45 is an apoptosis inducer demonstrating cytotoxic activity against the MCF-7 cell line. It initiates apoptosis in these cells via the mitochondrial pathway by increasing the Bax/Bcl-2 ratio, leading to the cleavage of caspase-9 and subsequent fragmentation of the DNA repair protein PARP. Additionally, Apoptosis inducer45 induces the cleavage of caspase-8, which subsequently triggers the cleavage of caspase-3 and its downstream target PARP, resulting in extrinsic apoptosis. This compound is applicable in breast cancer research.

Research Area

Cell Biology, Epigenetics & Chromatin, Molecular Biology, Protein Biochemistry

Key Properties

• Target: Caspase,Bcl-2 Family,PARP,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Caspase,Bcl-2 Family,PARP,Apoptosis