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Apoptolidin

SKU: orb1985124

Description

Apoptolidin is a natural product from Nocardiopsis bacteria that selectively induces apoptosis in transformed glial cells by potently inhibiting mitochondrial F1FO-ATPase (Ki ~4-5 µM). It serves as a valuable research tool for studying cancer cell metabolism and has demonstrated antibiotic and antifungal properties in vitro.

Research Area

Cell Biology, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number194874-06-1
MW1129.385
FormulaC58H96O21
SMILES[H][C@]1(C[C@H](OC)[C@@H](O)CC\C=C(/C)\C=C/[C@@H](O[C@@H]2O[C@@H](C)[C@H](OC)[C@@H](O)[C@@H]2O)[C@H](C)\C=C(/C)\C=C(\C)/C=C(C)/C(=O)O1)[C@@H](O)[C@]1(O)O[C@H](C[C@H](COC)O[C@H]2C[C@](C)(O)[C@@H](O[C@H]3C[C@@H](OC)[C@H](O)[C@@H](C)O3)[C@H](C)O2)[C@H](C)[C@H](O)[C@H]1C |c:10,13,31,37,t:34|
TargetApoptosis,ATPase,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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    1 mg
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Key Properties

No computed properties available.

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Apoptolidin (orb1985124)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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