Apicularen B

SKU: orb2564195

Description

Apicularen B is a cytotoxic macrolide and potent V-ATPase inhibitor isolated from the myxobacterium Archangium gephyra. This compound is a valuable research tool for investigating V-ATPase function in areas such as osteopetrosis, cancer, and bone resorption, applicable in both in vitro and in vivo studies.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 220757-06-2
• MW: 644.71
• Formula: C₃₃H₄₄N₂O₁₁
• SMILES: O=C1C=2C(C[C@]3(C[C@@H](O[C@H]4[C@H](NC(C)=O)[C@@H](O)[C@H](O)[C@@H](CO)O4)C[C@@](O3)(C[C@H](C/C=C/NC(/C=C\C=C/CC)=O)O1)[H])[H])=CC=CC2O
• Target: Proton pump

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

10627958