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API-1

SKU: orb1218099

Description

API-1 is a potent inhibitor of Akt. It induces GSK3-dependent, β-TrCP- and FBXW7-mediated Mcl-1 degradation, resulting in induction of apoptosis .

Images & Validation

Key Properties

CAS Number36707-00-3
MW337.29
Purity>98% (HPLC)
FormulaC13H15N5O6
SMILESC1=C(C(=O)C2=C(N=CN=C2N1[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O)N)C(=O)N
TargetAkt
SolubilityDMSO:10 mM

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

NSC177223

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Protocol Information

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500 mg
200 mg
5 mg
$ 390.00
10 mg
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25 mg
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100 mg
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