Apalutamide-13C-d3

SKU: orb2281022

Description

Apalutamide-13C-d3 is a stable isotope-labeled analog of the androgen receptor antagonist Apalutamide. This compound is utilized as an internal standard in LC-MS/MS for the quantitative analysis of Apalutamide in biological matrices, supporting pharmacokinetic and metabolic studies in prostate cancer research.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• MW: 481.45
• Formula: 13C C₂₀H₁₂F₄N₅O₂SD₃
• SMILES: FC(F)(F)C1=C(C#N)N=CC(N2C(C3(CCC3)N(C4=CC(F)=C(C(N[13C]([2H])([2H])[2H])=O)C=C4)C2=S)=O)=C1
• Target: Androgen Receptor
• Solubility: DMSO:40 mg/mL (83.08 mM)

Bioactivity

• Target IC50:
  AR:16 nM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

RN-509-13C,d3, RN509-13C,d3

Compound Identifiers

PubChem CID

163322426