Antitumor photosensitizer-4

SKU: orb2277745

Description

Antitumor Photosensitizer-4 (compound 10b), a conjugate of dasatinib and imatinib, serves as a potent tyrosine kinase inhibitor (TKI) targeting ABCG2. This photosensitizer (PS) induces apoptosis and reactive oxygen species (ROS) production, while demonstrating significant phototoxicity against both HepG2 and B16-F10 cells.

Images & Validation

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Key Properties

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MW	1269.9
Formula	C₆₅H₇₇ClN₁₂O₁₁S
Target	BCRP,Apoptosis

Storage & Handling

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Storage	-20°C
Disclaimer	For research use only

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Gene Symbol

BCRP,Apoptosis

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