Antitumor agent-61

SKU: orb1982890

Description

Antitumor agent-61 (Compound 9b) is an Irinotecan derivative exhibiting potent in vitro anticancer activity (IC50 0.92-3.23 μM) against multiple human cancer cell lines. It induces apoptosis in SK-OV-3 cells through mitochondrial pathways, supporting its investigation in oncology research for studying chemotherapeutic mechanisms and drug resistance.

Research Area

Cell Biology

Images & Validation

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Key Properties

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CAS Number	2408917-12-2
MW	992.08
Formula	C₅₄H₆₃FN₅O₁₀P
SMILES	CCOP(=O)(OCC)C(Nc1ccc(CCCC(=O)OC2(CC)C(=O)OCc3c2cc2-c4nc5ccc(OC(=O)N6CCC(CC6)N6CCCCC6)cc5c(CC)c4Cn2c3=O)cc1)c1ccc(F)cc1
Target	Apoptosis,Others

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

162645608 ↗

Key Properties

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No computed properties available.

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