Antitumor agent-61

SKU: orb1982890

Description

Antitumor agent-61 (Compound 9b) is an Irinotecan derivative exhibiting potent in vitro anticancer activity (IC50 0.92-3.23 μM) against multiple human cancer cell lines. It induces apoptosis in SK-OV-3 cells through mitochondrial pathways, supporting its investigation in oncology research for studying chemotherapeutic mechanisms and drug resistance.

Research Area

Cell Biology

Key Properties

• CAS Number: 2408917-12-2
• MW: 992.08
• Formula: C₅₄H₆₃FN₅O₁₀P
• SMILES: CCOP(=O)(OCC)C(Nc1ccc(CCCC(=O)OC2(CC)C(=O)OCc3c2cc2-c4nc5ccc(OC(=O)N6CCC(CC6)N6CCCCC6)cc5c(CC)c4Cn2c3=O)cc1)c1ccc(F)cc1
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

162645608