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Antitumor agent-210

SKU: orb3210012

Description

Antitumor agent-210 (Compound 1778) acts as an NK cell activator. It weakly enhances the proliferation of NK 92 cells and significantly boosts their activation and degranulation, thereby increasing their ability to kill tumor cells. Additionally, Antitumor agent-210 stimulates the release of cytokines granzyme B, perforin, and IFN-γ. It also reduces the number of metastatic lesions in mouse lungs and can be utilized in studies of melanoma lung metastasis.

Images & Validation

Key Properties

CAS Number2978670-53-8
MW543.99
FormulaC28H30ClNO8
SMILESC[C@]12C(C=3C(C=C(/C=C/[C@H](CC)C)N([C@@H](CCC(O)=O)C(O)=O)C3)=C(Cl)C1=O)=C(C(/C(=C/C)/C)=O)C(=O)O2
TargetIFNAR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information