Antitumor agent-138

SKU: orb2566975

Description

Antitumor agent-138 (compound 5b) is a tubulin polymerization inhibitor targeting the colchicine site, exhibiting potent antiproliferative activity (IC50 = 1.87 μM in MCF-7 cells). It induces G2/M arrest, apoptosis, and demonstrates anti-metastatic and anti-angiogenic properties in vitro, supporting its investigation in cancer research.

Research Area

Cell Biology, Signal Transduction

Images & Validation

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Key Properties

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CAS Number	2975168-22-8
MW	367.40
Formula	C₂₀H₂₁N₃O₄
SMILES	O=C(C1=CC(OC)=C(OC)C(OC)=C1)N2N=C(N)C=C2C=3C=CC(=CC3)C
Target	Apoptosis,Microtubule Associated

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

170836269 ↗

Key Properties

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No computed properties available.

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