Antitumor agent-101

SKU: orb1944297

Description

Antitumor agent-101 is a potent and selective covalent inhibitor of the lysine methyltransferases G9a and GLP, with IC50 values of 8.5 nM and 5.5 nM, respectively. It demonstrates antitumor activity in a PANC-1 xenograft model, making it a valuable chemical probe for epigenetic cancer research in both cellular and animal studies.

Research Area

Epigenetics & Chromatin, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2848632-52-8
• MW: 482.62
• Formula: C₂₆H₃₈N₆O₃
• SMILES: N(C=1C2=C(C=C(OCCCN3CCCC3)C(OC)=C2)N=C(N(C(C=C)=O)C)N1)C4CCN(C)CC4
• Target: Glucagon Receptor,Histone Methyltransferase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

168476152