Antipyrine

SKU: orb1310338

Description

Antipyrine (Phenazone) is an analgesic and antipyretic agent historically used in oral and topical formulations. It is now primarily employed as a probe substrate in pharmacological research to investigate hepatic cytochrome P450 enzyme activity and assess drug-drug interactions in both in vitro and in vivo studies.

Research Area

Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 60-80-0
• MW: 188.23
• Purity: 99.93% (May vary between batches)
• Formula: C₁₁H₁₂N₂O
• SMILES: Cc1cc(=O)n(-c2ccccc2)n1C
• Target: COX,Others,GABA Receptor
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (21.25 mM);Ethanol:36 mg/mL (191.26 mM);DMSO:110 mg/mL (584.39 mM);H2O:35 mg/mL (185.94 mM)

Bioactivity

• In Vitro:
  Antipyrine is an analgesic and antipyretic.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

COX, Antipyrine, antipyretic, analgesic, Inhibitor, inhibit, oxidative, probe, Phenazon, Phenazone

Compound Identifiers

PubChem CID

2206