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Antiproliferative agent-72

SKU: orb3136907

Description

Antiproliferative agent-72 (Compound 10) is an Hsp90 inhibitor with a dissociation constant (Kd) of 11 nM. It exhibits antiproliferative activity with IC50 values of 1.5 μM and 1.1 μM against HCT116 and NCI-N87 cells, respectively. Antiproliferative agent-72 is suitable for cancer research applications.

Research Area

Metabolism Research, Signal Transduction

Images & Validation

Key Properties

CAS Number1052646-54-4
MW434.34
FormulaC20H17Cl2N3O2S
SMILESClC1=CC(Cl)=C2C=C1OCCCCOC3=CC=CC(SC4=NC(=NC2=C4)N)=C3
TargetHSP

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information