Antiproliferative agent-64

SKU: orb2814536

Description

Antiproliferative agent-64 is a potent small molecule inhibitor of eIF4E that disrupts mRNA secondary structure to block translation. It selectively targets oncogenic mRNAs like c-Myc (EC50=1.2 nM) and inhibits proliferation in MDA-MB-231 breast cancer cells (EC50=7 nM), supporting its use in cancer research and translational studies.

Research Area

Cell Biology, Molecular Biology, Signal Transduction

Key Properties

• CAS Number: 1139263-21-0
• MW: 500.54
• Formula: C₂₉H₂₈N₂O₆
• SMILES: O[C@]12[C@]([C@@H]([C@@H](C(N(C)C)=O)[C@H]1O)C3=CC=CC=C3)(OC=4C2=C(OC)C=C(OC)C4)C5=CC=C(C#N)C=C5
• Target: DNA/RNA Synthesis,Microtubule Associated

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

71455198