Antiproliferative agent-57

SKU: orb2665121

Description

Antiproliferative agent-57 (M2) is a non-cytotoxic small molecule inhibitor of tumor angiogenesis with an IC50 of 0.68 μM in SiHa cells. It functions by suppressing hypoxia-induced VEGF secretion via modulation of the PI3K/AKT/mTOR and MAPK pathways, leading to reduced HIF-1α expression, as demonstrated in cellular and tissue-based research models.

Research Area

Cardiovascular Research, Epigenetics & Chromatin, Metabolism Research, Signal Transduction

Images & Validation

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Key Properties

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Target	Akt,mTOR,PI3K,p38 MAPK,VEGFR,HIF/HIF Prolyl-Hydroxylase

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Gene Symbol

Akt,mTOR,PI3K,p38 MAPK,VEGFR,HIF/HIF Prolyl-Hydroxylase

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