Antiproliferative agent-22

SKU: orb2566980

Description

Antiproliferative agent-22 is a research compound demonstrating in vitro antiproliferative activity against breast cancer cell lines, including MCF-7, MDA-MB-231, and MDA-MB-468. It is utilized in cancer research to study mechanisms of cell growth inhibition.

Research Area

Signal Transduction

Key Properties

• CAS Number: 1374305-45-9
• MW: 307.3
• Purity: 99.65% (May vary between batches)
• Formula: C₁₇H₁₃N₃O₃
• SMILES: N(\NC(=O)C=1C=CN=CC1)=C\2/C=3C(C(=O)C(C)=C2)=CC=CC3O
• Target: NF-κB

Bioactivity

• Target IC50:
  MDA-MB-468 cells:3.3 μM|MCF-7 cells:6.2 μM|MDA-MB-231 cells:3.3 μM
• In Vitro:
  Antiproliferative agent-22 exhibits antiproliferative activity against MCF-7, MDA-MB-231, and MDA-MB-468 cells, with IC50 values of 6.2 μM, 3.3 μM, and 3.3 μM, respectively.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

NF-κB, NFκB, NF-kB, NFkB

Compound Identifiers

PubChem CID

136264073