Antiparasitic agent-39

SKU: orb3175191

Description

Antiparasitic agent-39 (Compound 14) is a selective antiparasitic derivative of Deferasirox that reduces mitochondrial membrane potential. It demonstrates antiparasitic activity against T. brucei, T. gambiense, L. Mexicana, T. gondii, B. divergens, and P. falciparum, with EC50 values of 4.2 nM, 10.4 nM, 52.0 nM, 17.0 nM, 41.2 nM, and 54.8 nM, respectively.

Key Properties

• CAS Number: 2568585-37-3
• MW: 809.39
• Formula: C₄₉H₅₀ClN₄O₃P
• SMILES: [Cl-].O=C(NCCCCCCCCCC[P+](C=1C=CC=CC1)(C=2C=CC=CC2)C=3C=CC=CC3)C4=CC=C(C=C4)N5N=C(N=C5C=6C=CC=CC6O)C=7C=CC=CC7O
• Target: Parasite,Mitochondrial Metabolism

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

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Gene Symbol

Parasite,Mitochondrial Metabolism