Antioxidant agent-8

• Catalog Number: orb1744865
• Category: Small Molecules
• Description: Antioxidant agent-8, an orally active compound, inhibits Aβ 1-42 deposition by preventing fibril aggregation (IC 50 = 11.15 µM) and aiding in fibril disaggregation (IC 50 = 6.87 µM). It counteracts Cu2+-induced Aβ 1-42 fibril aggregation and disaggregation with lower IC 50 values of 3.69 µM and 3.35 µM, respectively. Additionally, it exhibits antioxidant and anti-inflammatory activities, demonstrates biosafety and blood-brain barrier permeability, and provides a neuroprotective effect.
• Purity: 98.00%
• MW: 248.23
• Biological Activity: Antioxidant agent-8 is an orally active compound that inhibits the deposition of Aβ 1-42 by preventing fibril aggregation (IC 50 =11.15 µM) and aiding in fibril disaggregation (IC 50 =6.87 µM). Moreover, it effectively counters Cu2+-induced Aβ 1-42 fibril aggregation and disaggregation, exhibiting lower IC 50 values of 3.69 µM and 3.35 µM, respectively. This compound also possesses antioxidant and anti-inflammatory activities, demonstrates biosafety and blood-brain barrier permeability, and offers a neuroprotective effect.
• Formula: C₁₃H₁₂O₅
• SMILES: C1COC(=C(C1=O)O)/C=C/C2=CC(=C(C=C2)O)O
• Storage: -20°C
• Note: For research use only