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Anticancer agent 39

Anticancer agent 39

Catalog Number: orb1983419

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Catalog Numberorb1983419
CategorySmall Molecules
DescriptionAnticancer Agent 39 (compound B12), a fluorescent derivative of Jiyuan Oridonin A (JOA), not only induces apoptosis through the collapse of mitochondrial membrane potential (MMP) but also inhibits cell cloning and migration, demonstrating promising anti-proliferative activity against HGC-27 cells with an IC50 value of 0.39 μM [1].
CAS Number2762426-00-4
Purity98.00%
MW896.08
SMILES[H][C@@]12C[C@H](O)[C@]3([H])[C@@]([C@@H]1O)(C(=O)C2=C)[C@@]1([H])C[C@]2([H])C(C)(C)CCC[C@@]32[C@H](OCCCc2cn(CCOCCOCCOCCN3C(=O)c4cccc5c(ccc(C3=O)c45)N3CCCCC3)nn2)O1
FormulaC50H65N5O10
Biological ActivityAnticancer Agent 39 (compound B12), a fluorescent derivative of Jiyuan Oridonin A (JOA), not only induces apoptosis through the collapse of mitochondrial membrane potential (MMP) but also inhibits cell cloning and migration, demonstrating promising anti-proliferative activity against HGC-27 cells with an IC50 value of 0.39 μM [1].
Storage-20°C
NoteFor research use only
Expiration Date12 months from date of receipt.
  • Antitumor agent-39 [orb1941766]

    98.00%

    159255-72-8

    732.01

    C40H69N5O7

    50 mg, 5 mg