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Anticancer agent 39

SKU: orb1983419

Description

Anticancer Agent 39 (B12) is a fluorescent JOA derivative that exhibits potent anti-proliferative activity against HGC-27 gastric cancer cells (IC50 = 0.39 µM). Its mechanism involves inducing apoptosis via mitochondrial membrane potential collapse and it further inhibits colony formation and cell migration in vitro.

Research Area

Cell Biology

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Key Properties

CAS Number2762426-00-4
MW896.08
FormulaC50H65N5O10
SMILES[H][C@@]12C[C@H](O)[C@]3([H])[C@@]([C@@H]1O)(C(=O)C2=C)[C@@]1([H])C[C@]2([H])C(C)(C)CCC[C@@]32[C@H](OCCCc2cn(CCOCCOCCOCCN3C(=O)c4cccc5c(ccc(C3=O)c45)N3CCCCC3)nn2)O1
TargetOthers,Apoptosis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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Anticancer agent 39 (orb1983419)

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