Anticancer agent 277

SKU: orb3173198

Description

Anticanceragent 277 (Compound 4a) is a potent anticancer agent with cytotoxic activity against cancer cells. It notably inhibits the proliferation of hepatocellular carcinoma cells by blocking the S phase and G2/M phase of the cell cycle. Additionally, it induces apoptosis through the generation of ROS and the upregulation of apoptosis-related proteins. In xenograft mouse models with HepG2 cells, Anticanceragent 277 effectively suppresses tumor growth.

Images & Validation

−

Key Properties

−

CAS Number	2673232-30-7
MW	340.34
Formula	C₁₈H₁₆N₂O₅
SMILES	O=C1N=C(NC=2C=CC=CC12)C(=O)C3=CC(OC)=C(OC)C(OC)=C3
Target	Apoptosis,Caspase,ROS,PARP,Akt

Storage & Handling

−

Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Quick Database Links

Gene Symbol

Apoptosis,Caspase,ROS,PARP,Akt

Documents Download

Datasheet

Product Information

Download

Request a Document

Protocol Information

Find More Protocols