Antibacterial agent 292

SKU: orb3173392

Description

Antibacterialagent 292 is a derivative of 3-pyrazolylindole and functions as an antibacterial agent. It exhibits potent inhibitory activity against Xanthomonas oryzae pv oryzae (Xoo) and Xanthomonas axonopodis pv citri (Xac), with EC50 values of 2.54 μg/mL and 3.49 μg/mL, respectively. It inhibits biofilm formation, bacterial motility, and extracellular polysaccharide production, induces morphological changes, promotes reactive oxygen species (ROS) accumulation, and leads to bacterial apoptosis. Additionally, it downregulates gene expression related to the type VI secretion system (T6SS). Antibacterialagent 292 can be applied in the management of bacterial leaf blight in rice and citrus canker.

Key Properties

• CAS Number: 3065015-86-0
• MW: 448.96
• Formula: C₂₄H₂₅ClN₆O
• SMILES: O=C(NC1=CC(=NN1)C2=CNC=3C=CC=CC32)CN4CCN(CC5=CC=C(Cl)C=C5)CC4
• Target: ROS,Apoptosis,Antibacterial

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

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Gene Symbol

ROS,Apoptosis,Antibacterial