Antibacterial agent 132

SKU: orb1962247

Description

This small molecule research compound exhibits potent antifungal activity against Candida parapsilosis (MIC90 <0.06 µg/mL) and Candida krusei (MIC90 62.50 µg/mL). It also functions as an aromatase inhibitor with an IC50 of 0.047 µM, making it a candidate for investigating fungal infections and hormone-dependent pathways in vitro.

Research Area

Infectious Disease & Virology, Metabolism Research

Key Properties

• CAS Number: 3026790-18-8
• MW: 444.94
• Purity: 98.00% (May vary between batches)
• Formula: C₂₄H₁₇ClN₄OS
• SMILES: ClC=1N=C2C=CC(OC)=CC2=CC1C=NNC3=NC(=CS3)C=4C=CC=C5C=CC=CC54
• Target: Antifungal,Cytochromes P450,Antibacterial
• Solubility: DMSO:55 mg/mL (123.61 mM)

Bioactivity

• Target IC50:
  NIH3T3 cells:10 μM
• In Vitro:
  Having cytotoxicity against the NIH/3T3 healthy cell line with an IC50 of 10 μM, Antibacterial agent 132 (compound 4j).

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Fungal

Compound Identifiers

PubChem CID

171340831