Anti-osteoporosis agent-11

SKU: orb2664993

Description

Anti-osteoporosis agent-11 (compound 3k) is a small molecule inhibitor of osteoclast differentiation (IC50 = 0.36 µM). It functions by suppressing RANKL-induced MAPK and NF-κB signaling, thereby reducing osteoclast formation, bone resorption, and related gene expression. This compound is a useful research tool for studying bone metabolism and osteoporosis mechanisms in cellular models.

Research Area

Signal Transduction

Key Properties

• CAS Number: 2869099-50-1
• MW: 497.31
• Formula: C₂₃H₁₇NO₂Se₂
• SMILES: O=C1C([Se]C=2C=CC=CC2)=C([Se]C=3C=CC=CC3)C(=O)N1CC=4C=CC=CC4
• Target: p38 MAPK,NF-κB,RANKL/RANK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172652599