Antcin K

SKU: orb3179742

Description

Antcin K is a selective inhibitor that targets the PI3K/Akt, NF-κB, MEK1/2-ERK, p38, and AP-1 pathways. It enhances IL-10 expression, thereby suppressing pro-inflammatory cytokine production, blocking monocyte adhesion, reducing tissue damage, and promoting myogenesis. Antcin K exhibits significant anti-inflammatory, anti-damage, and tissue-protective activities. It is primarily studied in the context of inflammatory-related diseases such as periodontitis, rheumatoid arthritis, and skeletal muscle injury.

Research Area

Cell Biology, Molecular Biology, Signal Transduction

Key Properties

• CAS Number: 741268-13-3
• MW: 488.67
• Formula: C₂₉H₄₄O₆
• SMILES: C[C@@]12C3=C([C@]4([C@](C)(CC3=O)[C@@]([C@@H](CCC(C(C(O)=O)C)=C)C)(CC4)[H])[H])[C@@H](O)C[C@]1([C@@](C)(O)[C@H](O)CC2)[H]
• Target: PI3K,NF-κB,DNA/RNA Synthesis,Akt,p38 MAPK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

PI3K,NF-κB,DNA/RNA Synthesis,Akt,p38 MAPK