Antazoline hydrochloride

SKU: orb1310946

Description

Antazoline hydrochloride

Research Area

Immunology & Inflammation, Infectious Disease & Virology, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2508-72-7
• MW: 301.82
• Purity: 99.76%
• Formula: C₁₇H₁₉N₃·HCl
• SMILES: C(N(Cc1ccccc1)c1ccccc1)C1=NCCN1
• Target: Histamine Receptor,HBV
• Solubility: 10% DMSO+40% PEG300+5% Tween-80+45% Saline:2 mg/mL (6.63 mM);DMSO:45 mg/mL (149.1 mM);Ethanol:4 mg/mL (13.25 mM);H2O:14 mg/mL (46.39 mM)

Bioactivity

• In Vivo:
  At a concentration of 30 μM, Antazoline effectively reduces neurotoxicity mediated by NMDA and also blocks NMDA-induced currents via a voltage-dependent and rapidly reversible action, with an inhibition rate of 85±3% at a voltage of -60 mV.
• In Vitro:
  In the model of sustained epileptic state induced by picrotoxin, Antazoline can be utilized to protect the intrinsic neural circuitry.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Antazoline, Antazoline HCl, Antazoline hydrochloride, Antazoline Hydrochloride, inhibit, Inhibitor, H1 receptor, HistamineReceptor, Histamine Receptor, Phenazocine HCl, Phenazoline, Phenazoline Hydrochloride, Phenazoline hydrochloride

Compound Identifiers

PubChem CID

2200