ANT308

SKU: orb3180336

Description

ANT308 is an antagonist of the vasoactive intestinal peptide (VIP receptor). It significantly enhances T cell activation and proliferation. By inhibiting VIP-VPAC2 signaling and reducing the expression of MCAM and N-cadherin, ANT308 suppresses melanoma cell migration and metastasis while inducing apoptosis. This compound is useful for research in acute myeloid leukemia (AML) and uveal melanoma (UVM).

Research Area

Cell Biology, Pharmacology & Drug Discovery

Key Properties

• Target: Apoptosis,PACAP
• CAS Number: 2871680-36-1
• MW: 3467.15
• Formula: C₁₅₆H₂₆₁N₄₇O₄₀S
• SMILES: C(N[C@@H](CC1=CC=C(O)C=C1)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC2=CC=C(O)C=C2)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC3=CC=C(O)C=C3)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(N)=O)C(O)=O)=O)CC(C)C)=O)[C@H](CC)C)=O)CC(C)C)=O)CC(N)=O)=O)CC(C)C)=O)=O)CCCCN)=O)CCCCN)=O)C(C)C)=O)C)=O)CCSC)=O)CCC(N)=O)=O)CCCCN)=O)CCCNC(=N)N)=O)CC(C)C)=O)CCCNC(=N)N)=O)[C@@H](C)O)=O)=O)CC(O)=O)=O)CO)=O)[C@@H](C)O)=O)(=O)[C@H]4N(C([C@@H](NC([C@@H](NC(=O)[C@H]5N(C([C@H](CCCCN)N)=O)CCC5)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCC4

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Apoptosis,PACAP