β-Amyloid (17-42)

SKU: orb2693225

Description

Amyloid 17-42 (Aβ(17-42)) is a major constituent of diffuse plaques in Alzheimer's disease and cerebellar pre-amyloid in Down's syndrome, derived by alpha- and gamma-secretase cleavage of the amyloid precursor protein (APP). Amyloid 17-42 can induce neuronal apoptosis via a Fas-like/caspase-8 activation pathway.

Research Area

Neuroscience

Key Properties

• Target: Amyloid-β
• CAS Number: 155178-13-5
• MW: 2577.1
• Purity: ≥95%
• Formula: C₁₁₉H₁₉₄N₂₈O₃₃S
• Protein Sequence: LVFFAEDVGSNKGAIIGLMVGGVVIA

Storage & Handling

• Expiration Date: 6 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Amyloid-β