Amisulpride

SKU: orb1310270

Description

Amisulpride (Solian) is a selective dopamine antagonist antipsychotic approved in Europe and Australia for schizophrenia and psychoses, and in Italy for dysthymia. It is utilized in research for investigating dopamine receptor function in both in vitro binding assays and in vivo behavioral models.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 71675-85-9
• MW: 369.48
• Purity: >99.99% (May vary between batches)
• Formula: C₁₇H₂₇N₃O₄S
• SMILES: C(NCC1N(CC)CCC1)(=O)C2=C(OC)C=C(N)C(S(CC)(=O)=O)=C2
• Target: 5-HT Receptor,Dopamine Receptor
• Solubility: H2O:< 1 mg/mL (insoluble or slightly soluble);DMSO:50 mg/mL (135.33 mM);Ethanol:65 mg/mL (175.92 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.41 mM)

Bioactivity

• Target IC50:
  D2 receptor:2.8 nM (Ki)|D3 receptor:3.2 nM (Ki)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Inhibitor, inhibit, Amisulpride, 5HT Receptor, 5HTReceptor, 5-HT, DAN2163, DAN-2163, DAN 2163, Dopamine, Dopamine Receptor, DopamineReceptor

Compound Identifiers

PubChem CID

2159