Amidate-VC-PAB-MMAF

SKU: orb1941642

Description

Amidate-VC-PAB-MMAF is a cleavable linker-payload conjugate used in antibody-drug conjugate (ADC) synthesis to minimize off-target cytotoxicity. It integrates a VC-PAB linker with the tubulin inhibitor MMAF for targeted cancer therapy research, supporting in vitro and in vivo preclinical studies for controlled drug release.

Key Properties

• CAS Number: 2202782-90-7
• MW: 1372.59
• Formula: C₆₉H₁₀₂N₁₁O₁₆P
• SMILES: [C@H]([C@H](C(N[C@@H](CC1=CC=CC=C1)C(O)=O)=O)C)(OC)[C@]2(N(C(C[C@H]([C@@H](N(C([C@@H](NC([C@@H](N(C(OCC3=CC=C(NC([C@@H](NC([C@@H](NC(=O)C4=CC=C(NP(OCC)(C#C)=O)C=C4)[C@@H](C)C)=O)CCCNC(N)=O)=O)C=C3)=O)C)C(C)C)=O)[C@@H](C)C)=O)C)[C@H](CC)C)OC)=O)CCC2)[H]
• Target: Drug-Linker Conjugates for ADC

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

164512669