AMI-408

SKU: orb2665240

Description

AMI-408 is a potent and selective PRMT1 inhibitor. It effectively diminishes asymmetric dimethylation of histone H4 at arginine 3 (H4R3me2a) in MLL-rearranged leukemia models. This tool compound is useful for investigating epigenetic mechanisms in cancer research, both in vitro and in vivo.

Research Area

Epigenetics & Chromatin

Key Properties

• CAS Number: 78866-14-5
• MW: 543.32
• Formula: C₂₀H₁₃Cl₂N₆NaO₅S
• SMILES: O=S([O-])(C1=C(N=NC2=CC=C(C=C2)OC)C(O)=C3C=CC(NC4=NC(Cl)=NC(Cl)=N4)=CC3=C1)=O.[Na+]
• Target: Histone Methyltransferase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

136180348