AMG2850

SKU: orb1310004

Description

AMG2850 is a selective, orally bioavailable TRPM8 antagonist. It is used in research to investigate the role of TRPM8 in cold sensation, pain, and cancer, with applications in both in vitro assays and in vivo animal models.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1470018-52-0
• MW: 417.35
• Purity: 99.84% (May vary between batches)
• Formula: C₁₉H₁₇F₆N₃O
• SMILES: C[C@H](NC(=O)N1CCc2cccnc2[C@H]1c1ccc(cc1)C(F)(F)F)C(F)(F)F
• Target: TRP/TRPV Channel
• Solubility: DMSO:100 mg/mL (239.61 mM);10% DMSO+90% Corn Oil:3.3 mg/mL (7.91 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

TRP Channel, Transient receptor potential channels, TRPVChannel, TRPChannel, TRPM8, TRPV Channel, AMG2850, AMG-2850, AMG 2850, inhibit, Inhibitor

Compound Identifiers

PubChem CID

90655362