AMG131

SKU: orb1298637

Description

AMG131 (CHS 131) is a selective PPARγ modulator for type 2 diabetes research. As a non-TZD compound, it is utilized in studies investigating insulin sensitization and glucose metabolism, with applications in both in vitro cellular assays and in vivo diabetic animal models.

Research Area

Metabolism Research, Molecular Biology

Key Properties

• CAS Number: 315224-26-1
• MW: 514.21
• Purity: 98.01% (May vary between batches)
• Formula: C₂₁H₁₂Cl₄N₂O₃S
• SMILES: Clc1ccc(c(Cl)c1)S(=O)(=O)Nc1cc(Cl)c(Oc2cnc3ccccc3c2)c(Cl)c1
• Target: PPAR
• Solubility: DMSO:27.5 mg/mL (53.48 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.89 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

diabetes, CHS 131, CHS-131, CHS131, activated, AMG131, AMG-131, AMG 131, inhibit, INT 131, INT131, INT-131, Inhibitor, mellitus, receptor, PPARγ, PPAR, Peroxisome proliferator-activated receptors, peroxisome, T2DM, SPPARM, proliferator

Compound Identifiers

PubChem CID

10229498