AMG-Tie2-1

SKU: orb1704853

Description

AMG-Tie2-1 is a dual Tie2 and VEGFR2 kinase inhibitor with demonstrated anticancer activity. It is a valuable research tool for studying angiogenesis in both cancer and cardiovascular disease contexts, with utility in in vitro and in vivo experimental models.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 870223-96-4
• MW: 479.45
• Purity: 98.90%
• Formula: C₂₅H₂₀F₃N₅O₂
• SMILES: O=C(NC1=CC=CC(=C1)C(F)(F)F)C2=CC=C(C(OC=3N=CC=CC3C4=NC(=NC=C4)NC)=C2)C
• Target: VEGFR
• Solubility: DMSO:150 mg/mL (312.86 mM)

Storage & Handling

• Storage: store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

VEGFR2, AMG-Tie2, AMGTie21, AMG-Tie-2-1, AMG-Tie2-1, AMG Tie2 1

Compound Identifiers

PubChem CID

16108977