AMG-221

SKU: orb1701208

Description

AMG-221 is a potent and selective inhibitor of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1). In diet-induced obese mice, it reduced fed blood glucose, insulin levels, and body weight. This small molecule is a valuable research tool for studying metabolic disorders, including type 2 diabetes and obesity, in both in vitro and in vivo models.

Research Area

Metabolism Research

Key Properties

• CAS Number: 1095565-81-3
• MW: 266.4
• Formula: C₁₄H₂₂N₂OS
• SMILES: N([C@@H]1[C@@]2(C[C@](C1)(CC2)[H])[H])C=3S[C@](C(C)C)(C)C(=O)N3
• Target: Dehydrogenase,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

135565424