Amentoflavone

SKU: orb1304220

Description

Amentoflavone is a biflavonoid research compound with inhibitory activity against key cytochrome P450 enzymes (CYP3A4, CYP2C9) and cathepsin B. It shows potential in studies for anti-inflammatory, antimalarial, and neuroreceptor-related research, based on in vitro data involving COX-2/iNOS downregulation and receptor binding assays.

Research Area

Cell Biology, Immunology & Inflammation, Infectious Disease & Virology, Metabolism Research, Neuroscience, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 1617-53-4
• MW: 538.46
• Purity: 98.21%
• Formula: C₃₀H₁₈O₁₀
• SMILES: Oc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)c(-c3cc(ccc3O)-c3cc(=O)c4c(O)cc(O)cc4o3)c2o1
• Target: Cytochromes P450,RSV,Antifungal,GABA Receptor,Reactive Oxygen Species,Apoptosis,Phospholipase,COX,Antibacterial,Opioid Receptor
• Solubility: Chloroform, Dichloromethane, Ethyl Acetate:Soluble;DMSO:34 mg/mL (63.14 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.71 mM)

Storage & Handling

• Storage: keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Disclaimer: For research use only

Alternative Names

PLA2, Respiratory syncytial virus, RSV, ReactiveOxygenSpecies, Reactive Oxygen Species, U-87 MG cells, γ-Aminobutyric acid Receptor, κ-opioid receptor, Didemethyl-ginkgetin, COX-2, COX, CYP2C9, CYP3A4, C-FLIP, 3',8''-Biapigenin, Amenthoflavone, Amentoflavone, Apoptosis, antibacterial, anti-inflammatory, Bacterial, orally active, Opioid Receptor, OpioidReceptor, NF-?B, Inhibitor, inhibit, Fungal, GABA Receptor, Gamma-aminobutyric acid Receptor, MCL1

Compound Identifiers

PubChem CID

5281600