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AMD 3465

SKU: orb1707672

Description

AMD 3465 is a potent and selective CXCR4 antagonist, inhibiting X4-tropic HIV-1 replication with low nanomolar IC50 values while being inactive against R5 viruses. It blocks CXCR4 ligand and antibody binding and is a valuable research tool for studying CXCR4 function in cancer metastasis, stem cell mobilization, and HIV entry in vitro.

Research Area

Cell Biology, Immunology & Inflammation, Infectious Disease & Virology, Pharmacology & Drug Discovery, Protein Biochemistry

Images & Validation

Key Properties

CAS Number185991-24-6
MW410.60
FormulaC24H38N6
SMILESN=1C=CC=CC1CNCC2=CC=C(C=C2)CN3CCNCCCNCCNCCC3
TargetHIV Protease,CXCR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information