Amcinonide

SKU: orb1310782

Description

Amcinonide (CL-34699) is a synthetic corticosteroid that acts as an agonist for glucocorticoid receptors. It is used in research to study anti-inflammatory and immunosuppressive mechanisms in both in vitro cellular assays and in vivo models of dermatological conditions.

Research Area

Cell Biology, Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 51022-69-6
• MW: 502.57
• Purity: 99.90% (May vary between batches)
• Formula: C₂₈H₃₅FO₇
• SMILES: [H][C@@]12C[C@@]3([H])[C@]4([H])CCC5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@@]1(OC1(CCCC1)O2)C(=O)COC(C)=O
• Target: Interleukin,Annexin A,NO Synthase,Glucocorticoid Receptor,TNF
• Solubility: 10% DMSO+90% Corn Oil:2.5 mg/mL (4.97 mM);DMSO:50 mg/mL (99.49 mM)

Bioactivity

• Target IC50:
  NO release:3.38 nM

Storage & Handling

• Storage: store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

AnnexinA, Annexin A, Annexin A1, Amcinonide, CL 34699, CL34699, CL-34699, GlucocorticoidReceptor, Glucocorticoid Receptor, Inhibitor, inhibit

Compound Identifiers

PubChem CID

443958