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AM404

SKU: orb1691433

Description

AM404 is a bioactive paracetamol metabolite that acts as an endocannabinoid reuptake inhibitor and TRPV1 activator. It exhibits neuroprotective and anticancer properties by blocking anandamide transport, inhibiting COX, NF-κB, and NFAT signaling. This activity reduces neuroblastoma cell migration and invasiveness in vitro and suppresses prostaglandin synthesis in microglia.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number183718-77-6
MW395.58
FormulaC26H37NO2
SMILESN(C(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)C1=CC=C(O)C=C1
TargetCannabinoid Receptor,Others,TRP/TRPV Channel

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

Protocol Information