AM12

SKU: orb1708063

Description

AM12 is a potent and selective inhibitor of the TRPC5 ion channel, effectively blocking its activation by lanthanides with an IC50 of 0.28 µM. This small molecule is a valuable research tool for studying TRPC5-mediated signaling in neurological and renal diseases, applicable in both cellular and animal models of pain and anxiety.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2387510-84-9
• MW: 349.13
• Formula: C₁₅H₉BrO₅
• SMILES: O=C1C=2C(OC(=C1O)C3=C(Br)C=CC=C3)=CC(O)=CC2O
• Target: TRP/TRPV Channel

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

137553166