AM-6761

SKU: orb1701214

Description

AM-6761 is a potent small molecule MDM2-p53 interaction inhibitor. It demonstrates significant antitumor efficacy in vivo, with an ED50 of 11 mg/kg in the SJSA-1 osteosarcoma xenograft model, supporting its use in cancer research targeting p53 pathways.

Key Properties

• CAS Number: 1584732-36-4
• MW: 695.69
• Formula: C₃₃H₃₇Cl₂FN₂O₅S₂
• SMILES: [C@H](CS(C(C)(C)C)(=O)=O)(N1[C@@H]([C@H](C[C@@](CC=2SC(CC(O)=O)=CN2)(C)C1=O)C3=CC(Cl)=CC=C3)C4=CC(F)=C(Cl)C=C4)[C@@H]5CC5
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

73386675