Aluminum Hydroxide

SKU: orb1308867

Description

Aluminum Hydroxide is a common orally active adjuvant primarily studied for its repository effect, pro-phagocytic activity, and its role in activating the NLRP3 inflammasome pathway. It is widely used in immunological research, both in vitro and in vivo, to investigate vaccine efficacy and innate immune responses.

Research Area

Immunology & Inflammation

Key Properties

• CAS Number: 21645-51-2
• MW: 78
• Formula: AlH₃O₃
• SMILES: [Al](O)(O)O
• Target: NOD-like Receptor (NLR),Others
• Solubility: DMSO:1 mg/mL (12.82 mM)

Bioactivity

• In Vivo:
  Administered orally at a dosage of 100 mg/kg/day for a duration of seven days, Aluminum Hydroxide enhances lipid peroxidation while simultaneously reducing the activity of Superoxide Dismutase (SOD) in the brain. Additionally, it is capable of dissolving in distilled water to form a homogeneous suspension .

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Aluminum, Aluminum Hydroxide, Inhibitor, inhibit

Compound Identifiers

PubChem CID

6328211