Alpelisib hydrochloride

• Catalog Number: orb1707687
• Category: Small Molecules
• Description: Alpelisib hydrochloride
• CAS Number: 1584128-91-5
• Purity: 98%
• MW: 477.93
• SMILES: CC1=C(C=2C=C(C(C(F)(F)F)(C)C)N=CC2)SC(NC(=O)N3[C@H](C(N)=O)CCC3)=N1.Cl
• Formula: C₁₉H₂₃ClF₃N₅O₂S
• Biological Activity: Alpelisib hydrochloride (BYL-719 hydrochloride) exhibits anticancer properties[1][2]. As a potent, selective PI3Kα inhibitor with high oral bioavailability, it demonstrates IC50 values of 5 nM for p110α, 250 nM for p110γ, 290 nM for p110δ, and 1200 nM for p110β, indicating its efficacy in targeting specific enzymes involved in cancer cell proliferation.
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.