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ALOX5 stabilizer-1

SKU: orb3173185

Description

ALOX5 stabilizer-1 is an inhibitor of arachidonic acid 5-lipoxygenase (ALOX5) with a Kd value of 7.26 μM. It reduces protein levels of β-catenin and subsequently inhibits the STAT3 signaling pathway. ALOX5 stabilizer-1 induces apoptosis in lung cancer cells and hampers their migration and proliferation, making it useful for research on non-small cell lung cancer (NSCLC).

Research Area

Cell Biology, Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

TargetSTAT,Wnt/beta-catenin,Lipoxygenase,Apoptosis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information