Alovudine

SKU: orb1302656

Description

Alovudine (3'-Deoxy-3'-fluorothymidine) is a thymidine analog that serves as a biomarker for DNA synthesis. Its utility in oncology research, particularly for pancreatic cancer, is enhanced by its reduced sensitivity to inflammatory backgrounds compared to 18F-FDG, making it suitable for in vivo PET imaging and in vitro proliferation assays.

Research Area

Cell Biology, Immunology & Inflammation, Infectious Disease & Virology, Molecular Biology

Key Properties

• CAS Number: 25526-93-6
• MW: 244.22
• Purity: 99.69% (May vary between batches)
• Formula: C₁₀H₁₃FN₂O₄
• SMILES: Cc1cn([C@H]2C[C@H](F)[C@@H](CO)O2)c(=O)[nH]c1=O
• Target: DNA/RNA Synthesis,Virus Protease,Antiviral
• Solubility: DMSO:55 mg/mL (225.21 mM);10% DMSO+40% PEG300+5% Tween-80+45% Saline:2.5 mg/mL (10.24 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Orthopoxvirus, DNA/RNA Synthesis, Alovudine, 3'Fluoro3'deoxythymidine, 3' Fluoro 3' deoxythymidine, 3'-Deoxy-3'-fluorothymidine, Antiviral, inhibit, Inhibitor

Compound Identifiers

PubChem CID

33039